Ipamorelin 5mg

Research background: Ipamorelin is a pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) studied as a selective agonist of the growth hormone secretagogue receptor (GHS-R1a) — the same receptor targeted by endogenous ghrelin. Activation of GHS-R1a on pituitary somatotroph cells triggers Gq/11-mediated signalling and intracellular calcium release, promoting GH granule exocytosis. Foundational research identified ipamorelin as notably selective among growth hormone secretagogues: unlike earlier GHRPs such as GHRP-6 and GHRP-2, it did not produce meaningful elevations in ACTH, cortisol, prolactin, FSH, LH, or TSH, even at doses substantially above its GH-releasing ED50. This selectivity profile is why it is frequently studied alongside GHRH analogues such as CJC-1295 to investigate complementary receptor pathways in GH release.

Literature: Raun et al., European Journal of Endocrinology (1998) — identification of ipamorelin as a selective GH secretagogue.

Storage

Store lyophilised peptide at -20°C, protected from light. Once reconstituted, store at 2-8°C and use within the timeframe indicated by your reconstitution protocol. Avoid repeated freeze-thaw cycles.

Frequently asked questions

How should this be stored?
Store lyophilised peptide at -20°C, protected from light. Once reconstituted, store at 2-8°C and use within the timeframe indicated by your reconstitution protocol.

Is this product tested for purity?
Purity: TBC. Batch-specific HPLC results will be published here once testing is complete.

Where can I find the Certificate of Analysis?
COA: TBC. We are finalising batch documentation and will publish this alongside HPLC results.

Is Ipamorelin suitable for human or veterinary use?
No. This product is sold strictly for in vitro laboratory research use only (RUO) and is not intended for human or animal consumption, diagnostic use, or any therapeutic application.

This product is intended for laboratory research use only (RUO). Not for human or veterinary use. Not a drug, food, or cosmetic. No health or therapeutic claims are made or implied.